Sergey Kiriuschenko first became known as a member of the Nyamiha-17 art collective that stirred up Minsk's art community in the late days of the Soviet Union, when they organized an exhibition in their studio on the 17th floor of a building in the Nyamiha district. During his 40 years of creative activity, Sergey investigated archaic art and cubist landscape, abstract forms, land art and conceptualism. His most recognizable works are images with 3D grids. In addition to surfaces, he works with sculpture, silkscreen, photography, video, land art and public art.
In 1977, he graduated from the Minsk Art Institute. Since 1983 he has been a member of the Belarusian Artists Council. In 2014, together with Alexei Borisenko and Sergey Shabohin, he founded the virtual collection of contemporary Belarusian art "KALEKTAR". At Vulica 2017, he provided the basis for the mural “Horizon Line 2”.